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VYNDAQEL is a prescription medicine used to treat adults with:

  • the cardiomyopathy of wild-type or hereditary transthyretin-mediated amyloidosis (ATTR-CM) to reduce death and hospitalization related to heart problems.

It is not known if VYNDAQEL is safe and effective in children.

Important Safety Information

What are the possible side effects of VYNDAQEL?

There were no known side effects that happened during treatment with VYNDAQEL in people with cardiomyopathy of transthyretin-mediated amyloidosis.

Before taking VYNDAQEL, tell your healthcare provider about all your medical conditions, including if you:

  • have liver problems.
  • are pregnant or plan to become pregnant. VYNDAQEL may harm your unborn baby. Tell your healthcare provider right away if you become pregnant or think you may be pregnant during treatment with VYNDAQEL. You may also report your pregnancy by calling the Pfizer reporting line at 1‑800‑438‑1985.
  • are breastfeeding or plan to breastfeed. You should not breastfeed during treatment with VYNDAQEL. It is not known if VYNDAQEL passes into your breast milk. Talk to your healthcare provider about the best way to feed your baby during treatment with VYNDAQEL.

Tell your healthcare provider about all the medicines you take including any prescription or over‑the‑counter medicines, vitamins, and herbal supplements.